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ACTIVATION

Sagittal Slice

Transverse Sl. Coronals Surface
R


L


BASELINE
R


L

Green or Blue are 2 to 3 standard deviations lower in perfusion
and white to white with black dot are 2 to 3 higher.
The site of the injury is the green area.


PROFILE

a.       40 year old ambidextrous female involved in a high speed motor vehicle accident as she was struck from behind by a drunk driver. She reported a brief episode of confusion following the accident and was treated for a wrist fracture that evening after a visit to the emergency room.

b.      Studies of the brain were not remarkable to report before the SPECT study. Neuropsychological testing revealed superior general memory function for visual and immediate auditory testing by low average range after a long delay on word list recall. She endorsed severe symptoms of depression and anxiety.

c.       Clinical problems initially included neck and back pain, mood liability with crying without obvious triggers, and lack of attention. 

d.      Litigation is pending.

e.       SPECT imaging revealed a focal decrease in activity in the left prefrontal area noted more prominently in the activation study. Also, a focal increase in the Thalamus in this study and the right Caudate and Insula in the baseline study was seen.

Treatment initially included physical therapy and chiropractic along with SSRI medication. This medication was felt to produce emotional indifference and was discontinued. A stimulant was added with a clinical report of improved concentration despite the neuropsychological testing. A short term trial with Galantamine and Rivastigmine was tired. An ongoing report of anxiety was then treated with SNRI medication with improvement and no emotional indifference symptoms

 


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